{"id":243,"date":"2017-07-17T17:48:00","date_gmt":"2017-07-17T22:48:00","guid":{"rendered":""},"modified":"2020-07-27T16:22:07","modified_gmt":"2020-07-27T21:22:07","slug":"243","status":"publish","type":"post","link":"https:\/\/underactivebladder.org\/index.php\/243\/","title":{"rendered":""},"content":{"rendered":"<div data-fid=\"1\" data-first=\"true\" style=\"background-color: white; border: 0px; color: #2e2e2e; display: inline; font-family: Arial, Helvetica, &quot;Lucida Sans Unicode&quot;, &quot;Microsoft Sans Serif&quot;, &quot;Segoe UI Symbol&quot;, STIXGeneral, &quot;Cambria Math&quot;, &quot;Arial Unicode MS&quot;, sans-serif; font-size: 13px; margin: 0px; padding: 0px; vertical-align: baseline;\">\n<h1 style=\"border: 0px; clear: both; color: inherit; font-size: 22px; font-weight: 400; line-height: 1.4; margin: 0px 0px 12px; padding: 0px; vertical-align: baseline;\">Re: Unravelling Detrusor Underactivity: Development of a Bladder Outlet Resistance-Bladder Contractility Nomogram for Adult Male Patients with Lower Urinary Tract Symptoms<\/h1>\n<ul style=\"border: 0px; display: inline; list-style: none; margin: 0px 0px 6px; padding: 0px; vertical-align: baseline;\">\n<li style=\"border: 0px; display: inline; margin: 0px; padding: 0px; vertical-align: baseline;\">Tomas L. Griebling,&nbsp;<span style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\">MD, MPH<\/span><\/li>\n<\/ul>\n<div style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/div>\n<div style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/div>\n<dl style=\"border: 0px; height: auto; margin: 12px 0px 0px; padding: 0px 0px 30px; vertical-align: baseline;\">\n<dd style=\"border: 0px; float: left; margin: 0px; padding: 0px; vertical-align: baseline; width: 431.2px;\"><\/dd>\n<dd style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline; word-wrap: break-word;\">http:\/\/dx.doi.org\/10.1016\/j.juro.2016.08.037<\/dd>\n<\/dl>\n<div style=\"border: 0px; clear: both; margin: 0px; padding: 0px; vertical-align: baseline;\">\n<dl style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/dl>\n<\/div>\n<div style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/div>\n<div style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\">\n<dl style=\"border: 0px; display: inline-block; font-size: 0.9em; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/dl>\n<\/div>\n<div data- style=\"border: 0px; display: inline; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/div>\n<\/div>\n<div data-fid=\"2\" style=\"background-color: white; border: 0px; color: #2e2e2e; font-family: Arial, Helvetica, &quot;Lucida Sans Unicode&quot;, &quot;Microsoft Sans Serif&quot;, &quot;Segoe UI Symbol&quot;, STIXGeneral, &quot;Cambria Math&quot;, &quot;Arial Unicode MS&quot;, sans-serif; font-size: 16px; margin: 0px; padding: 0px; vertical-align: baseline;\">\n<div style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\"><\/div>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\">M. Oelke, K. L. Rademakers and G. A. van Koeveringe; FORCE Research Group, Maastricht and Hannover<\/div>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\"><em style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\">Department of Urology, Hannover Medical School, Hannover, Germany, and Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands<\/em><\/div>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\"><span data-locatorkey=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26235823\" data-locatortype=\"url\" style=\"border: 0px; display: inline; margin: 0px; padding: 0px; vertical-align: baseline; white-space: pre-wrap; word-break: break-all; word-wrap: break-word;\">Neurourol Urodyn 2015; Epub ahead of print<\/span><em style=\"border: 0px; margin: 0px; padding: 0px; vertical-align: baseline;\">.<\/em><span data-locatorkey=\"http:\/\/dx.doi.org\/10.1002\/nau.22841\" data-locatortype=\"url\" style=\"border: 0px; display: inline; margin: 0px; padding: 0px; vertical-align: baseline; white-space: pre-wrap; word-break: break-all; word-wrap: break-word;\">doi: 10.1002\/nau.22841<\/span><\/div>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\">Abstract available at&nbsp;<span data-locatorkey=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26235823\" data-locatortype=\"url\" style=\"border: 0px; display: inline; margin: 0px; padding: 0px; vertical-align: baseline; white-space: pre-wrap; word-break: break-all; word-wrap: break-word;\"><a data-itrprs=\"Y\" data-url=\"\/science\/RedirectURL?_method=externObjLink&amp;_locator=url&amp;_cdi=273470&amp;_issn=00225347&amp;_origin=article&amp;_zone=art_page&amp;_targetURL=http%253A%252F%252Fwww.ncbi.nlm.nih.gov%252Fpubmed%252F26235823\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26235823\" style=\"border: 0px; color: #316c9d; margin: 0px; padding: 0px; text-decoration: none; vertical-align: baseline;\" target=\"externObjLink\" rel=\"noopener noreferrer\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26235823<\/a><\/span><\/div>\n<h2 style=\"border: 0px; clear: both; color: #5c5c5c; font-size: 18px; font-weight: 100; line-height: inherit; margin: 18px 0px 6px; padding: 0px; vertical-align: baseline;\">Editorial Comment<\/h2>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\">Underactive bladder is gaining increased attention as a clinical entity that tends to occur predominantly in older adults. Symptomatically this condition most often manifests as urinary retention with incomplete bladder emptying. The condition can also be associated with other lower urinary tract symptoms such as urinary urgency, frequency, nocturia and poor urinary stream. In men this condition can be challenging to differentiate from symptoms caused by bladder outlet obstruction. Detrusor underactivity, a component of the underactive bladder syndrome, has not been clearly defined from a physiological perspective.<\/div>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\">This study was conducted to create a nomogram for voiding parameters initially in a cohort of healthy men 40 years or older without voiding abnormalities. The model was then verified using retrospective analysis of urodynamic data from 822 older men with voiding dysfunction. Based on this analysis, measurements below the 25th percentile were associated with clinical indicators of detrusor underactivity. This finding provides an initial urodynamic measure that can be used to help differentiate detrusor underactivity from bladder outlet obstruction. Detrusor underactivity was associated with increased age, bladder capacity and post-void residual volume, and poorer voiding efficiency. These data can be used to help in the ongoing process of defining this complex clinical entity and as a predictive variable outcome measure in future research.<\/div>\n<div style=\"border: 0px; clear: both; margin-bottom: 9px; padding: 0px; vertical-align: baseline; word-spacing: -0.15ex;\"><\/div>\n<div itemprop=\"articleBody\" style=\"color: black; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 13.2px; line-height: 1.4; position: relative; width: 570px;\"><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022534716310229\" style=\"-webkit-font-smoothing: antialiased; border-radius: 4px; border: 1px solid rgba(0, 0, 0, 0.14902); box-shadow: none; box-sizing: border-box; color: #757575; cursor: pointer; display: block; font-family: sans-serif; font-size: 12px; font-weight: 700; line-height: 1rem; margin-bottom: 0px; margin-right: 0.5rem; margin-top: 24px; min-width: 50px; outline: 0px; padding: 12px 17px 10px; text-align: center; text-decoration: none; text-transform: uppercase; vertical-align: top; width: 647px;\" target=\"_blank\" rel=\"noopener noreferrer\">VISIT WEBSITE<\/a><\/p>\n<div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Re: Unravelling Detrusor Underactivity: Development of a Bladder Outlet Resistance-Bladder Contractility Nomogram for Adult Male Patients with Lower Urinary Tract Symptoms Tomas L. Griebling,&nbsp;MD, MPH http:\/\/dx.doi.org\/10.1016\/j.juro.2016.08.037 M. Oelke, K. L. Rademakers and G. A. van Koeveringe; FORCE Research&#8230; <a class=\"read-more\" href=\"https:\/\/underactivebladder.org\/index.php\/243\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[39],"tags":[19,14,16,15,17,18],"class_list":["post-243","post","type-post","status-publish","format-standard","hentry","category-research-articles","tag-bladder-outlet-obstruction","tag-detrusor-underactivity","tag-lower-urinary-tract-dysfunction","tag-underactive-bladder","tag-urinary-retention","tag-urodynamics"],"_links":{"self":[{"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/posts\/243","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/comments?post=243"}],"version-history":[{"count":1,"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/posts\/243\/revisions"}],"predecessor-version":[{"id":416,"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/posts\/243\/revisions\/416"}],"wp:attachment":[{"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/media?parent=243"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/categories?post=243"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/underactivebladder.org\/index.php\/wp-json\/wp\/v2\/tags?post=243"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}